Tuesday, 28 November 2017

Infertility Treatment Market - Global Industry Size, Share and Growth, 2023

Infertility is a condition where, a person is unable to reproduce by natural means. Treatment of the infertility depends on the cause of the condition. The various causes of infertility include sexually transmitted infections, genetic problems, DNA damage due to smoking, diabetes mellitus, and toxins such as chemical dusts, glues and pesticides. According to the Center for Disease Control and Prevention (CDC), there are around 6.9 million women aged 15-44 years, who have ever used infertility services. The global infertility treatment market is increasing significantly due to the changing lifestyle and exposure to harmful chemicals via pollution.


On the basis of procedure, the infertility treatment market is segmented into assisted reproductive technology (ART), artificial insemination, fertility surgeries, and other procedures such as egg freezing, sperm freezing, and embryo freezing. Assisted reproductive technology (ART) held the largest share of the market in 2016, due to the technological advancements and high prevalence of lifestyle disorders which is further leading to a decline in the fertility rate.

infertility treatment market is expected to grow significantly during the forecast period (2017-2023). The major factors driving growth of the infertility treatment market are continuous decline in fertility rates, high prevalence of lifestyle disorders, growing public awareness about infertility and the available treatment options, and technological advancements in infertility treatment devices.

Smoking is one of the major reasons for the decline in fertility rates and high prevalence of lifestyle disorders. According to the Center for Disease Control & Prevention (CDC), smoking kills more than 480,000 people every year in the U.S. Smoking reduces fertility in female ovocytes and in male sperm. As per the reports of World Health Organization (WHO), every year tobacco kills more than 7 million people worldwide. Thus, the various disorders caused by the smoking and decline in the fertility rate are driving the growth of the infertility treatment market.


Some of the key players in the infertility treatment market include Cooper Companies Inc., Cook Group Incorporated, Vitrolife AB, Genea Limited, Irvine Scientific, The Baker Company, Inc., IVFtech ApS, Esco Micro Pte. Ltd., Thermo Fisher Scientific, Inc., and Labotect GmbH.

Medical Tapes and Bandages Market Analysis, Size, Growth and Opportunities, 2023

Medical Tapes are used as a medicine and first aid to hold a bandage or other dressing onto a wound. These tapes are designed to hold firmly to skin, dressing materials, and underlying layers of the skin (due to the presence of adhesive), without damaging the skin, and allow air to pass through them and reach the skin. Some breathable tapes such as Kinesiology Tape, and other elastic bandages with adhesives, are made of cotton. Surgical tape is often white because it contains zinc oxide, which is added to prevent infections. The global medical tapes and medical bandages market, is expected to grow in the forecast period due to increasing number of surgeries and growth in aging population. Medical bandages are generally used to support a medical device such as dressing or splint or to restrict the movement of any part of the body. Some of the other medical tapes used include micropore paper tape, trans-pore polyethylene tape and zinc oxide tape.


The medical tapes and bandages market is divided on the basis of product, application and end user. On the basis of product, the market is segmented into medical tapes and bandages. Further types of medical bandages include gauze bandages, adhesive bandages, cohesive and elastic bandages, and other medical bandages. Medical tapes are further segmented as fabric tapes, paper tapes, plastic tapes, and other medical tapes. Medical bandages held the largest share of the global medical tapes and bandages market, in 2016, due to high number of surgical procedures, increasing aging population, and a rise in the number of various medical conditions that require surgical intervention.


The rise in the number of surgeries performed, rapid growth in geriatric population and rising cases of chronic wounds are the factors driving the growth of the medical tapes and bandages market, during the forecast period. According to the United Nations Department of Economic and Social Affairs (UN-DESA) report on the global aging population, the population of people aged 60 years or above is growing at a high rate. The number of people aged 60 years or over is projected to grow by 56.0 % globally, i.e. from 901 million in 2015 to 1.4 billion by 2030, and is projected to more than double its size of 2015, to reach 2.1 billion by 2050. Additionally, according to the World Bank, 30,537 surgeries were performed per 100,000 population, in the U.S., in 2012. Similarly, in 2015, number of surgical procedures performed in Australia was 28,907, per 100,000 population. According to a publication by the World Health Organization (WHO), in 2016, around 266.2 to 359.5 million surgeries were performed, globally, in 2012.


Some of the other key players operating in the medical tapes and bandages market are Beiersdorf AG, Covidien PLC (Medtronic PLC), Johnson & Johnson, Smith & Nephew PLC, Medline Industries, Inc., B. Braun Melsungen AG, Cardinal Health, Inc., Nitto Denko Corporation, BSN Medical GmbH (A Part of Svenska Cellulosa Aktiebolaget (SCA)) and Derma Sciences, Inc. (Integra Lifesciences Holdings Corporation).

Monday, 6 November 2017

Immune Checkpoint Inhibitors Market - Pipeline Analysis, Growth and Demand, 2023

The global immune checkpoint inhibitors market is expected to witness significant growth as these are proven to be more effective therapy in shrinking tumor in higher proportion of patients, as compared to other immunotherapies. Immune checkpoint inhibitors are applicable to a wider range of tumor types such as advanced or metastatic non-small cell lung cancer, renal cancer and melanoma. These inhibitors lower the rate of severe toxicities and immune-mediated side-effects. These are also convenient to administer and yield a good response rate of any single-agent immunotherapy.


Immune checkpoints comprised of cytotoxic T-lymphocyte antigen 4 (CTLA-4) inhibitors and PD-1 and PD-L1 inhibitors. CTLA-4 drug are molecules used to regulate, stimulate or inactivate the immune cells. PD-1 is found on the surface of cancer cells and it is used by tumors to evade the immune system; therefore, PD-1 inhibitor blocks PD-1 action and enables the body to attack and kill cancer cells. PD-L1 is a transmembrane protein of 40kDa that helps in suppressing the immune system during tissue allograft, pregnancy, autoimmune disease, hepatitis and other diseases.


Immune checkpoint inhibitors are showing good efficacy with PD-1 and PD-L1 inhibitors and CTLA-4 inhibitors. Yervoy, an anti-CTLA-4 product of Bristol-Myers Squibb Company got approved in the year 2011. The increased use of combination therapy of PD-1 and PD-L1 inhibitors represent a new signal of immunotherapeutics, which is expected to alter the standard of care for cancer across the globe. However, the development of effective immunotherapy presents some challenges due to complex pathophysiology of cancer and difficulty in managing treatment related toxic effects, which is expected to hamper the growth of the global market to some extent.


Some of the key players operating in the global market are Merck & Co., Inc., Bristol-Myers Squibb Company, AstraZeneca plc, Pfizer Inc., F. Hoffmann-La Roche AG, Novartis AG, Regeneron Pharmaceuticals, Inc., Ono Pharmaceutical Co., Ltd., and TG Therapeutics, Inc.

NASH Therapeutics Market - Global Industry Analysis, Size, Growth and Demand, 2023

The global nonalcoholic steatohepatitis therapeutics market is expected to witness significant growth due to current unmet medical need of NASH, scarcity of the permanent treatment of the disease, increasing prevalence of obesity, and high demand for safe and effective medication. The regulatory bodies are supporting the NASH market by providing designations and funding for speeding up the drug development process. In March 2015, obeticholic acid, an investigational Phase III clinical trial drug candidate of Intercept Pharmaceuticals Inc., received breakthrough therapy designation from the U.S. Food and Drug Administration for the treatment of patients with NASH.


The pipeline of NASH therapeutics is rich with more than 50 drugs. The pharmaceutical companies are actively involved in the research and development of drug for NASH. In June 2016, The Zydus Cadila initiated Phase III clinical trials of Saroglitazar to study its effect in adult NASH patients.

NASH is a type of liver disease, which is characterized by liver inflammation and fat accumulation, in the absence of significant alcohol consumption. It is the more severe form of nonalcoholic fatty liver disease. In NASH, fat accumulation, hepatic inflammation and hepatic triglyceride accumulation may ultimately lead to liver cirrhosis. North America is an emerging epidemic of obesity due to NASH. According to the NIH, NASH affects 2% to 5% of Americans and it is one of the major causes of cirrhosis.


A large number of pharmaceutical companies are investing huge capital for the development of NASH therapeutics. However, certain factors such as unknown etiology, complex pathophysiology, and high treatment cost of NASH are expected to hamper the growth of the global market during the forecast period.

Some of the key players operating in the global NASH therapeutics market are Genfit SA, Gilead Sciences, Inc., Novo Nordisk A/S, Intercept Pharmaceuticals, Inc., Enzo Biochem, Inc., Raptor Pharmaceutical Corp., Conatus Pharmaceuticals Inc., Zydus Cadila Healthcare Limited., Novartis AG, and Shire plc.

Friday, 3 November 2017

Blood Collection Market Outlook, Trends, Analysis and Growth, 2023

The global blood collection market is witnessing considerable growth due to increasing geriatric population, increasing number of accidental cases and growing surgical procedures. Moreover, growing prevalence of chronic diseases including cancer, cardiovascular disease, infectious diseases, autoimmune diseases, diabetes mellitus, and infectious diseases is supporting the growth of the market. Based on product type, the blood collection needle and syringe segment lead the market. The increasing demand of needle and syringe for blood collection across the globe, owing to their easy availability and ease of use, is driving the growth of this segment. In addition, rising initiatives undertaken by government associations to boost awareness about blood donations and advanced features of blood collection products are also supporting to the growth of this market.


The use of RFID technology in blood banks and transfusion medicine has the potential to improve operational efficiency. It helps in providing patient safety at point of care by automatically identifying, reconciling, and tracking blood products throughout the blood supply chain. The increasing use of radiofrequency identification (RFID) and needle free devices is expected to create opportunities for the manufacturers of blood collection products. However, risk associated with blood transfusions and growing needlestick injuries are the key factors hampering the growth of the global market.


The key players operating in the global blood collection market are Abbott Laboratories Inc., Becton, Dickinson and Company, Terumo Corporation, Sarstedt AG & Co., Nipro Medical Corporation, Qiagen, Haemonetics Corporation, Greiner Holding AG and F.L. Medical SRL.

Cartilage Repair Market - Global Industry Size, Trends and Growth, 2023

The global cartilage repair market is witnessing considerable growth due to increasing geriatric population, increasing obesity, increasing healthcare expenditure, and growing sports related injuries. Moreover, increase in innovative product launches and growth of medical tourism leading to awareness about the cartilage treatment modalities across the globe is supporting the growth of the market. Based on the treatment modalities, cell-based approaches segment is expected to grow at the fastest rate during the forecast period, due to long term results of this treatment.


The rapid growth in emerging economies and technological advancement in cartilage repair and regeneration products is expected to create opportunities for the manufacturers of cartilage repair products across the globe. However, the high cost of these products and lack of reimbursement for these treatments are the key factors hampering the growth of the global market.

Obesity is a serious health concern in the U.S. The increasing prevalence of obesity is driving the growth of the cartilage repair market in the U.S. According to CDC, during 2011-2012, 35.1% of adult aged 20 years or above were obese. In addition, as published by the Organization for Economic Cooperation and Development (OECD) in the year 2014, the obesity rate in Germany increased from 11.5% in 1999 to 14.7% in 2009. This increase in obesity rate leads to increase in demand for liposuction procedures, which is further accelerating the market growth.


The key players operating in the global cartilage repair market are Zimmer Biomet Holdings, Inc., Johnson & Johnson, Vericel Corporation, Smith & Nephew PLC, Osiris Therapeutics, Inc., RTI Surgical, Conmed Linvatec, B. Braun Melsungen AG, Anika Therapeutics S. R. L.  and Arthrex, Inc.

Cold Pain Therapy Market - Global Industry Trends and Forecast to 2023

The global cold pain therapy market is witnessing considerable growth due to increasing geriatric population, increasing healthcare expenditure and growing awareness about cold pain therapy products. Moreover, increase in innovative product launches, increase in road accidents and sport related injuries across the globe is supporting the growth of the market. Based on product, the OTC based product segment lead the global cold pain therapy market owing to its easy availability over the counter, without any doctor prescription and ease of use. The popularity of cold pain therapy products is due to presence of several pain relief products in market. These products include creams, gels, ointments, sprays, cold packs, rolls, cooling towels, motorized and non-motorized devices. Based on application, the musculoskeletal disorders segment lead the global market due to increasing cases of arthritis, osteoarthritis, joint pain and back pain across the globe.


The rapid growth in emerging economies and technological advancement in development of more effective products is expected to create further growth opportunities for the manufacturers of cold pain therapy products. However, high cost of prescription based products, lack of reimbursement and health hazards associated with the usage of cold therapy products are the key factors hampering the growth of the global market. 


Geographically, North America has been the largest market for cold pain therapy, owing to increased awareness, and easy accessibility to advanced technologies including motorized and non-motorized devices. Moreover, increasing incidence of musculoskeletal conditions drives the market growth in the region. The U.S. contributed largest revenue to the North American as well as global cold pain therapy market. The presence of large pool of patients with back pain, muscular pain and arthritis is the key driving factor of the U.S. cold pain therapy market.


The key players operating in the global cold pain therapy market are Johnson & Johnson, Sanofi, 3M Company, Hisamitsu Pharmaceutical Co., Inc., Rohto Pharmaceutical Co., Ltd., Medline Industries, Inc., Beiersdorf AG, Breg, Inc., Ă–ssur HF and DJO Finance LLC.