The
global oropharyngeal
cancer therapeutics market is expected to have significant
growth since the pipeline for oropharyngeal cancer is growing rapidly. Also,
there are no specific drugs available for the treatment of oropharyngeal
cancer providing increased opportunities for the major key players.
Oral
cavity tumor or oral tumor, is tumor that begins in the mouth (also known as
the oral cavity). Oropharyngeal malignancy begins in the oropharynx, which is
the part of the throat behind the mouth. The oral cavity comprises of lips, the inside
lining of the lips and cheeks (buccal
mucosa), the teeth, the gums, the front two-thirds of the tongue, the
floor of the mouth below the tongue and the bony roof of the mouth (hard
palate). The area behind the wisdom teeth, called the retromolar trigone is also sometimes
included in the oral cavity, though it is often considered part of the
oropharynx.
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The
diagnosis for oropharyngeal cancer is done in various steps. The first step is
physical examination, blood tests followed by complete head and neck
examination. Head and neck examination includes, indirect pharyngoscopy and
laryngoscopy, direct pharyngoscopy and laryngoscopy and panendoscopy. The
confirmation is done by biopsy which includes, exfoliative cytology, incisional
biopsy and fine needle
aspiration (FNA) biopsy. Various imaging tests such as CT scans, X- rays, MRI
and PET scans are also done for the diagnoses. The options available in the
market for treatment of oropharyngeal cancer include, surgery, chemotherapy,
radiation therapy, targeted therapy and palliative treatment.
The oropharyngeal
cancer therapeutics market is segmented based on the therapy which includes
surgery, chemotherapy, radiation therapy, targeted therapy and palliative
treatment. Chemotherapy holds the largest share since it contains maximum
number of drugs including, Cisplatin, Carboplatin, 5-fluorouracil (5-FU),
Paclitaxel (Taxol) and Docetaxel (Taxotere). The palliative treatment segment
holds the second largest share including, ibuprofen, acetaminophen, morphine or similar
drugs. Targeted therapy holds the lowest share and includes only one drug,
Cetuximab which may be combined with radiation therapy.
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Some of the key players operating in the oropharyngeal cancer therapeutics
market
include Genticel S.A., AstraZeneca Plc, Kolltan
Pharmaceuticals Inc., PNP Therapeutics Inc., Novartis AG, Advaxis Inc., Merck & Co. Inc., VLPbio and Synta
Pharmaceuticals Corp.
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