Tuesday, 9 January 2018

Latin America Scar Treatment Market - Global Regional Analysis, Top Manufacturers, Demand till 2023

The Latin America scar treatment market size was valued at $677.2 million in 2016, which is expected to attain $1,225.0 billion by 2023, growing at a CAGR of 8.9% during the forecast period (2017-2023). Topical scar treatment held the largest share of the market in 2016, ahead of surface, laser, injectable, and invasive surgical treatments. Scar treatment for keloid & hypertrophic scar is expected to witness the highest growth during forecast period in the regional market mainly due to increasing number of dermal injuries in the region.


Hospitals were the largest end user in the scar treatment market in Latin America and are expected to witness the highest growth, as compared to the private clinics, pharmacies & drug stores, and e-commerce in Latin America scar treatment market.

The demand for scar treatment in Latin America has been growing, mainly due to increasing awareness and consciousness about appearance among people in the region. The growth in the region is expected to be concentrated around Brazil, due to increasing demand of scar treatment products in the country. Additionally, the disposable income in Brazil has been increasing, due to which the affordability for such procedures has also increased. It has been also observed that the number of aesthetic plastic surgeries performed in the country for various purposes, including scar treatment has also been increasing. According to the International Society of Aesthetic Plastic Surgery (ISAPS), 461,544 cosmetic surgeries were performed in Mexico in 2016, the third highest in the world after the U.S. and Brazil and 907,913 non-surgical procedures were performed in Mexico, the fourth highest in the world after the U.S., India and Brazil, thus driving the growth of the Latin America market.


The key players are focusing on gel based scar treatment in the Latin America market. For instance, Medgel is an advanced line of silicone gel, offered by Silimed Inc., for treatment or prevention of scars, hypertrophic scars and keloid. Similarly, GC Aesthetics, recently launched Silgel direct to the consumers for the first time. Silgel is a silicone gel based, product for the treatment of hypertrophic and keloidal scars.

Some of the key players operating in the Latin America scar treatment market include Advanced Biotechnologies Inc., Scar Heal Inc., Silimed Inc., Natura Cosméticos S.A., Grupo Biomayan, Biodermis Cosmetics Ltd., GC Aesthetics PLC, Humco Holding Group, Inc., Farmoquimica S.A.

Monday, 8 January 2018

Europe Sleeping Aids Market Analysis, Size, Growth and Demand, 2022

The European sleeping aids market was valued at $14.8 billion in 2015 and is forecasted to grow at a CAGR of 6.2% during 2016-2022. Various sleep disorders are hampering the lives of people in the region, due to increasing tobacco and alcohol consumption, rising aging population, growing population base working in night shifts and changing lifestyle habits of the Europeans. Sleep disorders such as insomnia, sleep apnea, restless legs syndrome, narcolepsy, sleep walking and others greatly affect the population base in the European region.


Sleeping aids namely mattress & pillow, sleep laboratories, medication, sleep apnea devices and others are largely used for the above-mentioned sleeping disorders. Mattress & pillows held the largest share in the European sleeping aids market and contributed 43% in 2015. Amongst all the sleep related problems people are being majorly affected by insomnia and sleep apnea in the Europe.

Increasing awareness about sleep disorders and risks associated with them, by various organizations such as the British Sleep Society and Survey Sleep Research Center has been driving the demand of the sleeping aids products in the region. According to the Eurostat, aging population is a long-term trend in the region, this is also a key factor driving the demand for sleeping aids in the region. The share of population aged 65 years and over is increasing in every European Union (EU) member state. During the period 2016 to 2080 the aging population is expected to account for a share of 29.1% of the EU-28 population compared to 19.2% in 2016.



Some of the key players operating in the European sleeping aids industry are Sanofi S.A., Koninklijke Philips N.V., GlaxoSmithKline PLC, Merck & Co. Inc., Pfizer Inc., Roche Holding AG, AstraZeneca plc, Becton, Dickinson and Company, Drive Medical Ltd., Somnomedics Gmbh and Cardinal Health.

Cleanroom Technology Market - Global Industry Trends, Analysis and Demand, 2023

Cleanroom technology market is forecasted to attain $5 billion value by 2023, growing at a CAGR of 5.7% during 2017-2023. The growth in the market is likely to be led by increased demand for certified products, rising healthcare expenditure, technological advancements in cleanrooms, rising demand from pharmaceutical, biotech, and medical devices industries, and favorable healthcare regulations.
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In terms of technology type, the cleanroom technology market has been categorized as equipment and consumables, where consumables occupied a larger share in the global market in 2016. Consumables are cheaper and do not involve any installation and maintenance cost, as compared to the equipment used in cleanrooms. The equipment used in cleanroom technology industry include heating, ventilating, and air conditioning (HVAC) systems, high-efficiency particulate air (HEPA) filters, fan filter units (FFUs), laminar air flow systems and biosafety cabinets, air diffusers and showers, and other equipment, among these the HVAC systems held the largest share in the market, in 2016.
Cleanroom technology products are mainly used in the pharmaceutical, biotechnology, and medical devices industries, with some of the other users being hospitals, research laboratories and academic institutions. Pharmaceutical industry contributed the largest share to the cleanroom technology market and its growth is mainly attributable to the presence of a large number of biopharmaceutical companies, which further leads to a high production of finished pharmaceutical products, worldwide.
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Globally, the key providers in the cleanroom technology market are launching new products to gain a larger market share. For instance, in September 2016, Clean Air Products Inc., a designing and manufacturing company for cleanroom systems, announced the launch of new touchscreen interface for its air showers - model CAP701KD-ST. The enhanced feature enables easier control of the cycle timings and program changes of its air showers. The HMI interface displays a visual instruction of where the air shower is in the cycle and also includes a countdown screen that informs occupants about the time remaining in the air shower.
Some of the other key players operating in the cleanroom technology market include M+W Group GmbH, E.I. du Pont de Nemours and Company, Kimberly-Clark Corporation, Taikisha Ltd., Azbil Corporation, Illinois Tool Works Inc., Ardmac Ltd., and Alpiq Group.

Thursday, 4 January 2018

Endometrial Cancer Therapeutics Market - Epidemiology Analysis, Size and Growth, 2023

Global endometrial cancer therapeutics market is expected to witness significant growth as there are less number of approved drugs for treatment of endometrial cancer, leading to an increased opportunity for the drug manufacturers. High prevalence of cancer and rising demand for safe and effective medications can be attributed as the major drivers of this market. The regulatory bodies such as USFDA and EMA are supporting the growth of the global market by providing increased funding, designations and grants for speeding up the drug development process.
Endometrial cancer is the malignancy that develops in the layers of the cells that forms endometrium, lining of uterus. The precise cause of endometrial cancer is still unknown but it is assumed that estrogen may be involved in developing endometrial cancer, as estrogen helps in the formation of the endometrial lining. Obesity, polycystic ovary syndrome, infrequent periods and history of endometrial polyps can increase the risk of endometrial cancer. Women with diabetes, high blood pressure or breast cancer are at a greater risk of having endometrial cancer. Abnormal vaginal bleeding, bleeding between periods or after menopause, lower abdominal cramps or clear vaginal discharge after menopause are some of the main symptoms of endometrial cancer.
Though, chemotherapy is projected to have the maximum share in the global endometrial cancer therapeutics market owing to high adoption rate of chemotherapy over surgical treatment and radiation therapy in oncology. Also, carboplatin and paclitaxel are recommended as chemotherapeutic agents for first line of therapy in majority of the cases, which increases demand for these products. FDA recently approved IXEMPRA (ixabepilone) for use in endometrial cancer treatment which is likely to increase the growth of market during in the future.
Geographically, North America is expected to be the largest market for endometrial cancer therapeutics treatment, owing to the large number of research and development activities ad high healthcare expenditure. Europe is expected to hold the second largest share in the global market owing to growing product availability in the region.
Some of the key players operating in the global endometrial cancer therapeutics market are AstraZeneca Plc., Novartis AG, Bristol-Myers Squibb Company, Pfizer, Inc. and R-Pharm-US LLC.

Esophageal Cancer Therapeutics Market - Epidemiology Analysis, Growth and Demand, 2023

Global esophageal cancer therapeutics market is expected to witness significant growth with an increasing awareness regarding cancer treatment and technological advancements. Also, high demand for safe and effective medications and rising prevalence of cancer are driving the growth of the global market. The regulatory bodies such as USFDA, EMA are supporting the growth of the global market by providing funding, designations and grants for speeding up the drug development process.

Esophageal cancer involves formation of malignant cells in the tissues of the esophagus. Esophagus is a muscular tube that enable food and liquids to move from the throat to the stomach. The main types of esophageal cancer are adenocarcinoma and squamous cell carcinoma. Adenocarcinoma forms in cells that produce and release mucus and other fluids. Squamous cell carcinoma forms in flat cells lining the esophagus. Esophageal squamous cell carcinoma includes heavy alcohol consumption and smoking as major risk factors, with gastroesophageal reflux disease and Barrett esophagus further contributing as the risk factors of esophageal adenocarcinoma. Esophageal cancer has no early signs or symptoms; therefore, an advanced stage diagnosis is difficult.


The marketed drugs for esophageal cancer treatment includes Ramucirumab (Cyramza), Docetaxel (Docefrez), and Trastuzumab (Herceptin) for adenocarcinoma. Also, XELIRI and FU-LV are combination drugs given along with the chemotherapy that contributes in the global esophageal cancer therapeutics market.

Genentech, Inc. markets Trastuzumab (Herceptin) in combination with cisplatin and a fluoropyrimidine (either capecitabine or 5-fluorouracil), for the treatment of patients with HER2-overexpressing metastatic gastric or gastroesophageal (GE) junction adenocarcinoma who were not treated for metastatic disease prior.

Certain chemotherapy medications such as Doxorubicin, Bleomycin, Vinblastine, Dacarbazine, Chlorambucil, Procarbazine Prednisolone, Mustine, Vincristine, Etoposide, Cyclophosphamide, Gemcitabine, Cisplatin and Cytarabine are well established as a conventional method. Immunotherapy, combination therapy, monoclonal antibodies and steroids have also been showing good results for the treatment of esophageal cancer.


Some of the key players operating in the global esophageal cancer therapeutics market include Genentech, Inc., Sanofi-Aventis, Eli Lilly and Company, Ono Pharmaceutical Co., Ltd., Merck & Co., Inc., Johnson & Johnson Pharmaceutical Research & Development, LLC, Gilead Sciences, and Bristol-Myers Squibb, among others.

Neuroendocrine Carcinoma Therapeutics Market - Global Industry Analysis, Growth and Demand, 2023

Global neuroendocrine carcinoma therapeutics market is witnessing significant growth due to large number of marketed drugs and Phase III drugs. Neuroendocrine carcinoma is a tumor that begins in neuroendocrine cells and can spread, or metastasize, to other parts of the body. It starts in the hormone producing cells of the body’s neuroendocrine system. Neuroendocrine tumors can begin in many organs including, lungs, brain and gastrointestinal tract. It is a very rare cancer with symptoms such as hyperglycemia, hypoglycemia, diarrhea, weight loss, pain, cough, lump formation, jaundice, unusual bleeding, headache and anxiety. The risk factors of developing neuroendocrine cancer includes, age, gender, family history, immune system suppression, arsenic exposure and sun exposure. The diagnosis can be done by normal physical examination followed by blood tests, urine tests, X- ray, CT scan, PET scan, MRI and biopsy.
The treatments available for neuroendocrine tumor include chemotherapy, surgery and radiation therapy. Chemotherapy comprises the drug’s use to destroy malignant cells by hindering the cells ability to divide and grow. Streptozocin (Zanosar) and 5-fluorouracil (Adrucil, 5-FU) are some of the drugs that are used to treat neuroendocrine tumors. Many pharmaceutical companies have been working continuously for the development of targeted therapy for the growth of neuroendocrine cancer market.

Geographically, neuroendocrine carcinoma therapeutics market has been segmented into North America, Europe, Asia Pacific and Rest of the World (RoW). According to Cancer.Net, approximately 8,000 people are identified with neuroendocrine cancer every year in the U.S. Several key players functioning in neuroendocrine carcinoma therapeutics market are based in the U.S and therefore consider North America as their main market for product launch and research and development investments. Also, entrenched infrastructure and favorable reimbursement scenario are the major factors accountable for the strengthening of North America’s neuroendocrine carcinoma therapeutics market. Europe is the second largest market for neuroendocrine carcinoma therapeutics, followed by Asia. Increasing prevalence of neuroendocrine cancer in Asia Pacific along with the refining economic scenario is expected to play an important role in driving the market growth in the region.
Some of the key players operating in the global neuroendocrine carcinoma therapeutics market include Pfizer Ltd., Eli Lilly & Company, Novartis AG, F. Hoffmann-La Roche Ltd., Ispen SA, Amgen, Inc., Callisto Pharmaceuticals Pvt. Ltd., Biosynthema, Inc., Teva Pharmaceuticals, Ltd. and Bristol-Myers Squibb among others.

Oropharyngeal Cancer Therapeutics Market Therapy, Growth and Forecast to 2023

The global oropharyngeal cancer therapeutics market is expected to have significant growth since the pipeline for oropharyngeal cancer is growing rapidly. Also, there are no specific drugs available for the treatment of oropharyngeal cancer providing increased opportunities for the major key players.
Oral cavity tumor or oral tumor, is tumor that begins in the mouth (also known as the oral cavity). Oropharyngeal malignancy begins in the oropharynx, which is the part of the throat behind the mouth. The oral cavity comprises of lips, the inside lining of the lips and cheeks (buccal mucosa), the teeth, the gums, the front two-thirds of the tongue, the floor of the mouth below the tongue and the bony roof of the mouth (hard palate). The area behind the wisdom teeth, called the retromolar trigone is also sometimes included in the oral cavity, though it is often considered part of the oropharynx.
The diagnosis for oropharyngeal cancer is done in various steps. The first step is physical examination, blood tests followed by complete head and neck examination. Head and neck examination includes, indirect pharyngoscopy and laryngoscopy, direct pharyngoscopy and laryngoscopy and panendoscopy. The confirmation is done by biopsy which includes, exfoliative cytology, incisional biopsy and fine needle aspiration (FNA) biopsy. Various imaging tests such as CT scans, X- rays, MRI and PET scans are also done for the diagnoses. The options available in the market for treatment of oropharyngeal cancer include, surgery, chemotherapy, radiation therapy, targeted therapy and palliative treatment.
The oropharyngeal cancer therapeutics market is segmented based on the therapy which includes surgery, chemotherapy, radiation therapy, targeted therapy and palliative treatment. Chemotherapy holds the largest share since it contains maximum number of drugs including, Cisplatin, Carboplatin, 5-fluorouracil (5-FU), Paclitaxel (Taxol) and Docetaxel (Taxotere). The palliative treatment segment holds the second largest share including, ibuprofen, acetaminophen, morphine or similar drugs. Targeted therapy holds the lowest share and includes only one drug, Cetuximab which may be combined with radiation therapy.
Some of the key players operating in the oropharyngeal cancer therapeutics market include Genticel S.A., AstraZeneca Plc, Kolltan Pharmaceuticals Inc., PNP Therapeutics Inc., Novartis AG, Advaxis Inc., Merck & Co. Inc., VLPbio and Synta Pharmaceuticals Corp.